IDE 2, endoderm formation inducer (RMML-00120173)
Cat. No.: RMML-00120173
Category: Inhibitors & Activators
INQUIRY
1 mg
Cell-permeable definitive endoderm formation inducer
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Cell-permeable definitive endoderm formation inducer; CAS Number: 1136466-93-7; Purity: > 98%; Soluble in water to 20 mM, in ethanol to 100 mM and in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Biological Description | Cell-permeable definitive endoderm formation inducer (EC50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo. |
|---|---|
| CAS Number | 1136466-93-7 |
| Chemical Name | 7-(2-Cyclopentylidenehydrazinyl)-7-oxoheptanoic acid |
| SMILES | C1CCC(=NNC(=O)CCCCCC(=O)O)C1 |
| Molecular Formula | C12H20N2O3 |
| Molecular Weight | 240.30 Da |
| PubChem Identifier | 23836158 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in water to 20 mM, in ethanol to 100 mM and in DMSO to 100 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
