Mouse F box only Protein 32(FBXO32) ELISA Kit (RMEK-0153723)
Cat. No.: RMEK-0153723
Category: ELISA Kits
INQUIRY
1 x 96 tests
This ELISA kit is a 1. 5 hour solid-phase ELISA designed for the quantitative determination of the targets. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
Product Features
| Species Reactivity | Mouse |
|---|---|
| Assay Time | 1.5 h |
Target Information
| Target Symbol | FBXO32 |
|---|---|
| UniProt ID | Q969P5 |
| Biomarker of SCs/CSCs | Hepatic Cancer |
| Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
| Cellular Localization | Cytoplasm. Nucleus. Shuttles between cytoplasm and the nucleus. |
| Involvement in Disease | Defects in FBXO32 are associated with susceptibility to dilated cardiomyopathy (DCM). A disorder characterized by ventricular and impaired systolic function, resulting in heart failure and arrhythmia. Patient are at risk of premature death. |
Storage & Shipping
| Storage | Store at 2-8°C |
|---|---|
| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
