Mouse GAS6 ELISA Kit (RMEK-0153746)
Cat. No.: RMEK-0153746
Category: ELISA Kits
INQUIRY
1 x 96 tests
Mouse GAS6 ELISA kit is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of Mouse GAS6 protein in mouse serum, plasma and cell culture supernatant. The technology. Quantitate Mouse GAS6 with 8.4 pg/mL sensitivity.
Product Features
| Species Reactivity | Mouse |
|---|---|
| Detection Method | Colorimetric |
| Assay Duration | One step assay |
| Assay Time | 1.5 h |
| Assay Type | Sandwich (quantitative) |
| Precision | Intra-Assay-Plasma-8-3.4%; Inter-Assay-Plasma-3-5% |
| Sensitivity | 8.4 pg/mL |
| Range | 78.13 pg/mL - 5000 pg/mL |
| Sample Type | Cell culture media, Cell culture supernatant, Cit plasma, EDTA Plasma, Hep Plasma, Serum |
| Recovery | Cell culture supernatant-106-100% - 118%; Serum-108-92% - 118%; Cell culture media-89-87% - 90%; Hep Plasma-83-67% - 99%; EDTA Plasma-108-103% - 116%; Cit plasma-105-94% - 114% |
| Key Features | One-wash 90 minute protocol; Sensitivity: 8.4 pg/mL; Range: 78.13 pg/mL - 5000 pg/mL; Sample type: Cell culture media, Cell culture supernatant, Cit plasma, EDTA Plasma, Hep Plasma, Serum; Detection method: Colorimetric; Assay type: Sandwich (quantitative); Reacts with: Mouse |
Target Information
| Target Symbol | GAS6 |
|---|---|
| UniProt ID | Q14393 |
| Function | Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. |
| Cellular Localization | Secreted. |
| Post-transcriptional Modifications | Isoform 1 is proteolytically processed after secretion to yield a N-terminal 36 kDa protein and a C-terminal 50 kDa protein including the laminin G-like domains which activates AXL.Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. |
Storage & Shipping
| Storage | Store at 2-8°C |
|---|---|
| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
