Mouse VCAM1 Antibody Pair - BSA and Azide free (RMAB-0252304)
Cat. No.: RMAB-0252304
Category: Antibody Pair
INQUIRY
10 x 96 tests
The Antibody Pair can be used to quantify Mouse VCAM1 (CD106). BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/mL as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results._x000D_
Product Features
| Conjugate | Unconjugated capture and detector antibodies |
|---|---|
| Species Reactivity | Mouse |
| Range | 23.4 pg/mL - 1500 pg/mL |
| Applications | Sandwich ELISA |
| Key Features | Unconjugated capture and detector antibodies; Adaptable to any antibody pair-based assay format; Antibody concentration ~ 1 mg/mL; BSA and azide free buffer - ready for conjugation; Reacts with: Mouse |
Target Information
| Target Symbol | VCAM1 |
|---|---|
| Target Name | Vascular cell adhesion protein 1 |
| UniProt ID | P19320 |
| Cellular Localization | Membrane. |
| Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
| Post-translational Modifications | Sialoglycoprotein. |
| Domain | Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion. |
| Sequence Similarities | Contains 7 Ig-like C2-type (immunoglobulin-like) domains. |
Storage & Shipping
| Storage & Shipping | Store at 4°C. Please refer to protocols. |
|---|
For research use only. Not for clinical use.
