Nifuroxazide, JAK/STAT signaling inhibitor (RMML-00120573)
Cat. No.: RMML-00120573
Category: Inhibitors & Activators
INQUIRY
100 mg
JAK/STAT signaling inhibitor. Nitrofuran antibiotic.
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | JAK/STAT signaling inhibitor. Nitrofuran antibiotic.; CAS Number: 965-52-6; Purity: > 98%; Soluble in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | JAK/STAT |
|---|---|
| Biological Description | JAK/STAT signaling inhibitor. Nitrofuran antibiotic. Inhibits JAK2 and Tyk2 phosphorylation and subsequent downstream STAT3 inhibition (EC50 = 3 μM). Antidiarrheal. Shows little effect on Akt, NF-κB, JAK1, MAPK and Src signaling. |
| CAS Number | 965-52-6 |
| Chemical Name | 4-Hydroxybenzoic acid 2-[(5-nitro-2-furanyl)methylene]hydrazide |
| Molecular Formula | C12H9N3O5 |
| Molecular Weight | 275.22 Da |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM |
| Storage & Shipping | Store at 4°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
