Recombinant Human CD59 Protein (RMPP-00230773)
Cat. No.: RMPP-00230773
Category: Growth Factors & Cytokines
Research Area: Signal Transduction
INQUIRY
20 μg
Customer Size
Product Features
| Source | CHO cells |
|---|---|
| Purity | > 98% SDS-PAGE. Greater than 98% by HPLC analyses. |
| Nature | Recombinant |
| Endotoxin Level | < 1.000 Eu/µg |
| Animal Free | No |
| Form | Lyophilized |
| Applications | SDS-PAGE; HPLC |
| Key Features | Expression system: CHO cells; Purity: > 98% SDS-PAGE; Endotoxin level: < 1.000 Eu/µg; Active: Yes; Suitable for: SDS-PAGE, Functional Studies, HPLC |
Protein Information
| UniProt ID | P18075 |
|---|---|
| Molecular Weight | 26 kDa |
| Sequence | MANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECA FPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSN VILKKYRNMVVRACGCH |
| Sequence Similarities | Belongs to the TGF-beta family. |
| Protein Length | Protein fragment |
| Cellular Localization | Secreted. |
| Tissue Specificity | Expressed in the kidney and bladder. Lower levels seen in the brain. |
| Developmental Stage | Expressed in the developing eye, brain and ear during embryogenesis. |
| Function | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. |
| Post-translational Modifications | Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
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For research use only. Not for clinical use.
