Recombinant Human Interferon gamma Protein (Active) (RMPP-00230028)
Cat. No.: RMPP-00230028
Category: Recombinant Protein
Research Area: Epigenetics and Nuclear Signaling
INQUIRY
100 μg
Customer Size
Product Features
| Purity | > 90% HPLC. |
|---|---|
| Nature | Synthetic |
| Animal Free | No |
| Form | Liquid |
| Applications | Blocking |
| Application Note | Blocking - Blocking peptide for Anti-DDX4 / MVH antibody |
| Key Features | Purity: > 90% HPLC; Suitable for: Blocking |
Protein Information
| UniProt ID | Q9NQI0 |
|---|---|
| Sequence Similarities | Belongs to the DEAD box helicase family. DDX4/VASA subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
| Cellular Localization | Cytoplasm. Cytoplasm, perinuclear region. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. |
| Tissue Specificity | Expressed only in ovary and testis. Expressed in migratory primordial germ cells in the region of the gonadal ridge in both sexes. |
| Function | Probable ATP-dependent RNA helicase required during spermatogenesis. Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request. |
|---|
For research use only. Not for clinical use.
