Recombinant Human TGF beta 1 Protein (Active) (RMPP-00230258)
Cat. No.: RMPP-00230258
Category: Recombinant Protein
Research Area: Signal Transduction
INQUIRY
5 μg
1 mg
Product Features
| Source | Baculovirus infected Sf9 cells |
|---|---|
| Nature | Recombinant |
| Animal Free | No |
| Tags | DDDDK tag N-Terminus, Avi tag C-Terminus |
| Conjugation | Biotin |
| Form | Liquid |
| Applications | Functional Studies; SDS-PAGE |
| Key Features | Expression system: Baculovirus infected Sf9 cells; Purity: = 90% SDS-PAGE; Active: Yes; Tags: DDDDK tag N-Terminus, Avi tag C-Terminus; Suitable for: Functional Studies, SDS-PAGE |
Protein Information
| UniProt ID | P27037 |
|---|---|
| Molecular Weight | 45 kDa including tags |
| Sequence Similarities | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 protein kinase domain. |
| Protein Length | Protein fragment |
| Cellular Localization | Membrane. |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. |
Storage & Shipping
| Shipping and Storage | Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle. pH: 8.00Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine), 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diolContains 8 ng/µL DDDDK peptide This product is an active protein and may elicit a biological response in vivo, handle with caution. |
|---|
For research use only. Not for clinical use.
