Recombinant Human Wnt5b Protein (RMPP-00230686)
Cat. No.: RMPP-00230686
Category: Kinases
Research Area: Signal Transduction
INQUIRY
2 μg
Customer Size
Product Features
| Source | Baculovirus infected Sf9 cells |
|---|---|
| Purity | > 80% Densitometry. Affinity purified. |
| Nature | Recombinant |
| Animal Free | No |
| Tags | proprietary tag N-Terminus |
| Modifications | mutated T460M |
| Form | Liquid |
| Applications | SDS-PAGE; Functional Studies |
| Key Features | Expression system: Baculovirus infected Sf9 cells; Purity: > 80% Densitometry; Active: Yes; Tags: proprietary tag N-Terminus; Suitable for: SDS-PAGE, Functional Studies |
Protein Information
| UniProt ID | Q14680 |
|---|---|
| Molecular Weight | 88 kDa including tags |
| Sequence | MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIIS QDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLID FGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLY VLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKK RISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQT MEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDI KSNNWSLEDVTASDKNYVAGLIDYDWCEDDLSTGAATPRTSQFTKYWTES NGVESKSLTPALCRTPANKLKNKENVYTPKSAVKNEEYFMFPEPKTPVNK NQHKREILTMPNRYTTPSKARNQCLKETPIKIPVNSTGTDKLMTGVISPE RRCRSVELDLNQAHMEETPKRKGAKVFGSLERGLDKVITVLTRSKRKGSA |
| Sequence Similarities | Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. Contains 1 KA1 (kinase-associated) domain. Contains 1 protein kinase domain. |
| Protein Length | Protein fragment |
| Cellular Localization | Cytoplasm. |
| Tissue Specificity | Expressed in placenta, kidney, thymus, testis, ovary and intestine. |
| Function | Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis. |
| Post-translational Modifications | Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8. |
Storage & Shipping
| Shipping and Storage | Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle. pH: 7.50Constituents: 0.79% Tris HCl, 25% Glycerol (glycerin, glycerine), 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.88% Sodium chloride, 0.002% PMSF This product is an active protein and may elicit a biological response in vivo, handle with caution. |
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For research use only. Not for clinical use.
