Recombinant rat IL-1 alpha Protein (RMPP-00230941)
Cat. No.: RMPP-00230941
Category: Growth Factors & Cytokines
Research Area: Signal Transduction
INQUIRY
2 μg
Customer Size
Product Features
| Source | E.coli |
|---|---|
| Purity | ≥ 98% SDS-PAGE. Sterile filtered. Greater than 98% pure by HPLC analyses. |
| Nature | Recombinant |
| Endotoxin Level | < 0.010 Eu/µg |
| Animal Free | Yes |
| Form | Lyophilized |
| Applications | WB; Cellular Activation; SDS-PAGE; HPLC |
| Key Features | Expression system: E.coli; Purity: ≥ 98% SDS-PAGE; Endotoxin level: < 0.010 Eu/µg; Active: Yes; Suitable for: WB, Cellular Activation, SDS-PAGE, HPLC |
Protein Information
| UniProt ID | P01133 |
|---|---|
| Molecular Weight | 6 kDa |
| Sequence | NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR |
| Sequence Similarities | Contains 9 EGF-like domains. Contains 9 LDL-receptor class B repeats. |
| Protein Length | Full length protein |
| Cellular Localization | Membrane. |
| Tissue Specificity | Expressed in kidney, salivary gland, cerebrum and prostate. |
| Function | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro. |
| Involvement in Disease | Hypomagnesemia 4 |
| Post-translational Modifications | O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor). |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
|---|
For research use only. Not for clinical use.
