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RepSox (RMML-00120868)

Cat. No.: RMML-00120868

Category: Inhibitors & Activators

INQUIRY 1 mg 5 mg
RepSox is a cell-permeable, selective inhibitor of the TGF-β type 1 receptor. This inhibitor demonstrates less potent activity. Enhances reprogramming of mouse embryonic fibroblasts. Direct lineage reprogramming of fibroblasts to mature neurons, in combination with CHIR99021, Valproic Acid, Forskolin, SP600125, Gö6983 and Y-27632. Alone or in combination with Forskolin, Dexamethasone, and Nicotinamide, induces differentiation of human pancreatic progenitor cells into insulin-producing cells.

Product Features

Purity ≥ 98%
Applications Differentiation, Reprogramming
Cross Reactivity Human, Mouse, Non-Human Primate, Other, Rat

Compound Information

Target Pathways Activin/Nodal/TGFβ
CAS Number 446859-33-2
Molecular Formula C₁₇H₁₃N₅

Storage & Shipping

Handling Refer to SDS for further information.

For research use only. Not for clinical use.