Sheep B lymphocyte antigen CD20(MS4A1) ELISA Kit (RMEK-0155566)
Cat. No.: RMEK-0155566
Category: ELISA Kits
INQUIRY
1 x 96 tests
This ELISA kit is a 1. 5 hour solid-phase ELISA designed for the quantitative determination of the targets. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
Product Features
| Species Reactivity | Sheep |
|---|---|
| Assay Time | 1.5 h |
Target Information
| Target Symbol | MS4A1 |
|---|---|
| UniProt ID | P11836 |
| Biomarker of SCs/CSCs | Skin Cancer |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor. Constitutively associated with membrane rafts. |
| Post-transcriptional Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Involvement in Disease | Immunodeficiency, common variable, 5 (CVID5): A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. The disease is caused by variants affecting the gene represented in this entry. |
Storage & Shipping
| Storage | Store at 2-8°C |
|---|---|
| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
