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SMADi Neural Induction Kit (RMMS-00560024)

Cat. No.: RMMS-00560024

Category: Specialized Medium Kits

Research Area: Disease Modeling, Drug Discovery and Toxicity Testing, Neuroscience, Stem Cell Biology

INQUIRY 1 Kit
Serum-free medium kit for highly efficient SMAD inhibition-mediated neural induction of human ES and iPS cells

Product Features

Cell Type Neural Cells, PSC-Derived, Pluripotent Stem Cells
Formulation Serum-Free
Applications Differentiation
Description SMADi Neural Induction Kit consists of a defined, serum-free medium and supplement for the highly efficient neural induction of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. This kit combines Neural Induction Medium with SMADi Neural Induction Supplement, which directs differentiation by blocking TGF-β/BMP-dependent SMAD signaling, resulting in efficient neural induction of even hard-to-differentiate cell lines. Neural progenitor cells (NPCs) can be generated using SMADi Neural Induction Kit with either an embryoid body (EB) protocol or monolayer culture protocol. The resulting cultures are enriched for central nervous system (CNS)-type NPCs, which express SOX1, Nestin, and PAX6. NPCs generated using this kit can be passaged as single cells and expanded in Neural Progenitor Medium. The NPCs can also be differentiated into neurons and glia. Learn how to generate neural progenitor cells from human pluripotent stem cells (hPSCs) in our On-Demand Neural Induction Course, and browse our Tech Tips on the Neural Induction of hPSCs using the Embryoid Body Method or Monolayer Method.

Storage & Shipping

Storage -20°C or colder
Shipping Shipped on gel packs.

For research use only. Not for clinical use.