5-Azacytidine (RMML-00120055)
Cat. No.: RMML-00120055
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity. Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem. Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A. Enhances differentiation to cardiomyocytes from human embryonic stem cells. Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
Product Features
| Purity | ≥ 95% |
|---|---|
| Applications | Differentiation, Reprogramming |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | Epigenetic |
|---|---|
| CAS Number | 320-67-2 |
| Molecular Formula | C₈H₁₂N₄O₅ |
Storage & Shipping
| Handling | Refer to SDS for further information. |
|---|
For research use only. Not for clinical use.
