AGK2 (RMML-00120076)
Cat. No.: RMML-00120076
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
AGK2 is a cell-permeable, reversible inhibitor of mammalian sirtuin 2. Its target, SIRT2, is a nicotinamide adenine dinucleotide. Decreases aldehyde dehydrogenase. Decreases SIRT2-induced autophagy in human cancer cell lines. Protects dopaminergic neurons from α-synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease.
Product Features
| Purity | ≥ 95% |
|---|---|
| Applications | Activation |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | Epigenetic |
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| Alternative Names | SIRT2 inhibitor |
| CAS Number | 304896-28-4 |
| Molecular Formula | C₂₃H₁₃Cl₂N₃O₂ |
| Molecular Weight | 434.3 Da |
Storage & Shipping
| Handling | Refer to SDS for further information. |
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For research use only. Not for clinical use.
