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A-674563 (RMML-00120061)

Cat. No.: RMML-00120061

Category: Inhibitors & Activators

INQUIRY 50 mg
A potent and selective AKT1 inhibitor

Product Features

Source Synthetic
Purity > 99%
Key Features A potent and selective AKT1 inhibitor ; CAS Number: 552325-73-2; Purity: > 99%; Soluble in DMSO to 50 mM; Form / State: Solid; Source: Synthetic

Compound Information

Biological Description A potent and selective AKT1 inhibitor,  Ki = 11 nM. Also inhibts PKA, CDK2, GSK3β and ERK2 (Ki values are 16, 46, 110, 260 nM respectively).
CAS Number 552325-73-2
Chemical Name (2S)-1-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy-3-phenylpropan-2-amine
SMILES CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CC=CC=C4)N
Molecular Formula C22H22N4O
Molecular Weight 358.44 Da
PubChem Identifier 11314340

Storage & Shipping

Handling Refer to SDS for further information.
Solubility Soluble in DMSO to 50 mM
Storage & Shipping Shipped at room temperature. Store at -20°C.

For research use only. Not for clinical use.