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Anti-alpha Actinin/ACTN1 Antibody

Anti-alpha Actinin/ACTN1 Antibody (RMAB-0250056)

Cat. No.: RMAB-0250056

Category: Primary Antibodies

INQUIRY 100 μL Customer Size
Mouse monoclonal to alpha Actinin/ACTN1

Product Features

Isotype IgG2a
Clonality Monoclonal
Host Species Mouse
Clone Number OTI7A4
Form Liquid
Purity Affinity purified
Species Reactivity Mouse, Rat, Human, African green monkey
Immunogen Recombinant fragment corresponding to Human alpha Actinin/ACTN1 aa 65-893. Protein produced in E.coli.
Applications WB, ICC/IF, IHC-P
Key Features Mouse monoclonal to alpha Actinin/ACTN1; Suitable for: WB, ICC/IF, IHC-P; Reacts with: Mouse, Rat, Human, African green monkey; Isotype: IgG2a

Target Information

Target Symbol ACTN1
Target Name Alpha-actinin-1
UniProt ID P12814
Cellular Localization Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle.
Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Sequence Similarities Belongs to the alpha-actinin family. Contains 1 actin-binding domain. Contains 2 CH (calponin-homology) domains. Contains 2 EF-hand domains. Contains 4 spectrin repeats.

Storage & Shipping

Storage Buffer pH: 7.30; Preservative: 0.02% Sodium azide; Constituents: PBS, 1% BSA, 50% Glycerol
Storage & Shipping Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.

For research use only. Not for clinical use.