Anti-Amino-terminal enhancer of split/AES Antibody (RMAB-0250065)
Cat. No.: RMAB-0250065
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to Amino-terminal enhancer of split/AES
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR8385 |
| Form | Liquid |
| Purity | Tissue culture supernatant |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | WB, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to Amino-terminal enhancer of split/AES; Suitable for: WB, ICC/IF; Knockout validated; Reacts with: Human |
Target Information
| Target Symbol | TLE5 |
|---|---|
| Target Name | TLE family member 5 |
| UniProt ID | Q08117 |
| Cellular Localization | Nucleus. |
| Function | Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. |
| Post-translational Modifications | Ubiquitinated by XIAP/BIRC4. |
| Domain | Lacks the C-terminal WD repeats. |
| Sequence Similarities | Belongs to the WD repeat Groucho/TLE family. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at -20°C. |
For research use only. Not for clinical use.
