Anti-CD11c Antibody (RMAB-0250187)
Cat. No.: RMAB-0250187
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to CD11c
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR21826 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Mouse |
| Immunogen | Recombinant fragment. |
| Applications | IHC-P, Flow Cyt |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD11c; Suitable for: IHC-P, Flow Cyt; Reacts with: Mouse |
Target Information
| Target Symbol | ITGAX |
|---|---|
| Target Name | Integrin alpha-X |
| UniProt ID | P20702 |
| Cellular Localization | Membrane. |
| Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
| Domain | The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. |
| Sequence Similarities | Belongs to the integrin alpha chain family. Contains 7 FG-GAP repeats. Contains 1 VWFA domain. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: PBS, 40% Glycerol, 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
