Anti-Tenascin C Antibody (RMAB-0251143)
Cat. No.: RMAB-0251143
Category: Primary Antibodies
INQUIRY
50 μg
100 μg
Mouse monoclonal to Tenascin C
Product Features
Isotype | IgG1 |
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Clonality | Monoclonal |
Host Species | Mouse |
Clone Number | EB2 |
Form | Liquid |
Purity | Protein G purified |
Species Reactivity | Human |
Immunogen | Purified Tenascin C from human fetal fibroblasts. |
Applications | IHC-Fr, WB |
Key Features | Mouse monoclonal to Tenascin C; Suitable for: IHC-Fr, WB; Knockout validated; Reacts with: Human; Isotype: IgG1 |
Target Information
Target Symbol | TNC |
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Target Name | Tenascin |
UniProt ID | P24821 |
Cellular Localization | Secreted > extracellular space > extracellular matrix. |
Function | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. |
Sequence Similarities | Belongs to the tenascin family. Contains 15 EGF-like domains. Contains 1 fibrinogen C-terminal domain. Contains 15 fibronectin type-III domains. |
Storage & Shipping
Storage Buffer | Preservative: 0.09% Sodium azide; Constituents: 1% BSA, PBS |
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Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.