Anti-CD14 Antibody (RMAB-0250216)
Cat. No.: RMAB-0250216
Category: Primary Antibodies
INQUIRY
10 μL
100 μL
Rabbit monoclonal to CD14
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR3652 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide within Human CD14 aa 1-1 (extracellular). The exact sequence is proprietary. |
| Applications | Flow Cyt, IHC-P |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD14; Suitable for: Flow Cyt, IHC-P; Reacts with: Human |
Target Information
| Target Symbol | CD14 |
|---|---|
| Target Name | Monocyte differentiation antigen CD14 |
| UniProt ID | P08571 |
| Cellular Localization | Cell membrane. |
| Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
| Post-translational Modifications | N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
| Sequence Similarities | Contains 11 LRR (leucine-rich) repeats. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 40% Glycerol (glycerin, glycerine), 0.05% BSA, 59% PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C. |
For research use only. Not for clinical use.
