Anti-CD14 Antibody (RMAB-0250217)
Cat. No.: RMAB-0250217
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to CD14
Product Features
Isotype | IgG |
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Clonality | Monoclonal |
Host Species | Rabbit |
Clone Number | EPR3653 |
Form | Liquid |
Purity | Protein A purified |
Species Reactivity | Human |
Immunogen | Synthetic peptide. |
Applications | WB, IHC-P |
Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD14; Suitable for: WB, IHC-P; Reacts with: Human |
Target Information
Target Symbol | CD14 |
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Target Name | Monocyte differentiation antigen CD14 |
UniProt ID | P08571 |
Cellular Localization | Cell membrane. |
Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
Post-translational Modifications | N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
Sequence Similarities | Contains 11 LRR (leucine-rich) repeats. |
Storage & Shipping
Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
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Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.