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Anti-CD14 Antibody (RMAB-0250217)

Cat. No.: RMAB-0250217

Category: Primary Antibodies

INQUIRY 100 μL Customer Size
Rabbit monoclonal to CD14

Product Features

Isotype IgG
Clonality Monoclonal
Host Species Rabbit
Clone Number EPR3653
Form Liquid
Purity Protein A purified
Species Reactivity Human
Immunogen Synthetic peptide.
Applications WB, IHC-P
Key Features Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD14; Suitable for: WB, IHC-P; Reacts with: Human

Target Information

Target Symbol CD14
Target Name Monocyte differentiation antigen CD14
UniProt ID P08571
Cellular Localization Cell membrane.
Function Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Post-translational Modifications N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
Sequence Similarities Contains 11 LRR (leucine-rich) repeats.

Storage & Shipping

Storage Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage & Shipping Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

For research use only. Not for clinical use.