Anti-CD14 Rabbit Monoclonal Antibody (RMAB-0251464)
Cat. No.: RMAB-0251464
Category: Primary Antibodies
Research Area: Immunology, Stem Cells
INQUIRY
100 μL
Customer Size
Anti-CD14 Rabbit Monoclonal Antibody. Tested in IF, WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Immunogen | Recombinant fragment. |
| Applications | WB, IHC, IF, ICC |
Target Information
| Target Symbol | CD14 |
|---|---|
| Target Name | Monocyte differentiation antigen CD14 |
| UniProt ID | P08571 |
| Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
| Post-translational Modifications | N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
| Sequence Similarities | Contains 11 LRR (leucine-rich) repeats. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
