Anti-CD20 Antibody – Mouse IgG2a (Chimeric) (RMAB-0250248)
Cat. No.: RMAB-0250248
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Mouse monoclonal to CD20 - Mouse IgG2a
Product Features
| Isotype | IgG2a |
|---|---|
| Clonality | Monoclonal |
| Host Species | Mouse |
| Clone Number | EP459Y |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | ICC, Flow Cyt (Intra), IP, WB |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Mouse monoclonal to CD20 - Mouse IgG2a; Suitable for: ICC, Flow Cyt (Intra), IP, WB; Knockout validated; Reacts with: Human |
Target Information
| Target Symbol | MS4A1 |
|---|---|
| Target Name | B-lymphocyte antigen CD20 |
| UniProt ID | P11836 |
| Cellular Localization | Membrane. |
| Function | This protein may be involved in the regulation of B-cell activation and proliferation. |
| Involvement in Disease | Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD2 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. |
| Post-translational Modifications | Phosphorylated. Might be functionally regulated by protein kinase(s). |
| Sequence Similarities | Belongs to the MS4A family. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
