Anti-CD38 Antibody - Extracellular domain (RMAB-0250333)
Cat. No.: RMAB-0250333
Category: Primary Antibodies
INQUIRY
100 μg
Customer Size
Mouse monoclonal to CD38 - Extracellular domain
Product Features
| Isotype | IgG1 |
|---|---|
| Clonality | Monoclonal |
| Host Species | Mouse |
| Clone Number | 5C5C3 |
| Form | Liquid |
| Purity | Protein G purified |
| Species Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human CD38 aa 1 to the C-terminus (extracellular). (Purified from E.coli). |
| Applications | IHC-P, WB |
| Key Features | Mouse monoclonal to CD38 - Extracellular domain; Suitable for: IHC-P, WB; Knockout validated; Reacts with: Human; Isotype: IgG1 |
Target Information
| Target Symbol | CD38 |
|---|---|
| Target Name | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
| UniProt ID | P28907 |
| Cellular Localization | Membrane. |
| Developmental Stage | Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E. |
| Function | Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. |
| Sequence Similarities | Belongs to the ADP-ribosyl cyclase family. |
Storage & Shipping
| Storage Buffer | Preservative: 0.05% Sodium azide; Constituent: 99% PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
