Anti-Nestin Antibody - Neural Stem Cell Marker (RMAB-0250891)
Cat. No.: RMAB-0250891
Category: Primary Antibodies
INQUIRY
100 μg
Customer Size
Rabbit polyclonal to Nestin - Neural Stem Cell Marker
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Purity | Immunogen affinity purified |
| Species Reactivity | Mouse |
| Immunogen | Synthetic peptide: ALETESQDSAEPSGSEE , corresponding to amino acids 1481-1497 of Human Nestin. |
| Applications | WB |
| Key Features | Rabbit polyclonal to Nestin - Neural Stem Cell Marker; Suitable for: WB; Reacts with: Mouse; Isotype: IgG |
Target Information
| Target Symbol | NES |
|---|---|
| Target Name | Nestin |
| UniProt ID | P48681 |
| Developmental Stage | Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments. |
| Function | Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. |
| Post-translational Modifications | Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized. |
| Sequence Similarities | Belongs to the intermediate filament family. |
Storage & Shipping
| Storage Buffer | Preservative: 0.01% Sodium azide; Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
