Anti-CD43 Antibody (RMAB-0250361)
Cat. No.: RMAB-0250361
Category: Primary Antibodies
INQUIRY
100 μL
1 mL
Rabbit monoclonal to CD43
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | SP55 |
| Form | Liquid |
| Purity | Protein A/G purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide within Human CD43 aa 2-3 (internal sequence). The exact sequence is proprietary. |
| Applications | ICC/IF, IHC-P, WB, Flow Cyt |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD43; Suitable for: ICC/IF, IHC-P, WB, Flow Cyt; Reacts with: Human |
Target Information
| Target Symbol | SPN |
|---|---|
| Target Name | Deformed epidermal autoregulatory factor 1 homolog |
| UniProt ID | P16150 |
| Cellular Localization | Membrane. |
| Function | One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. |
| Post-translational Modifications | Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures. |
Storage & Shipping
| Storage Buffer | pH: 7.60; Preservative: 0.1% Sodium azide; Constituents: PBS, 1% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C. |
For research use only. Not for clinical use.
