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Anti-DDX3 Antibody (RMAB-0250504)

Cat. No.: RMAB-0250504

Category: Primary Antibodies

INQUIRY 100 μL Customer Size
Rabbit monoclonal to DDX3

Product Features

Isotype IgG
Clonality Monoclonal
Host Species Rabbit
Clone Number EPR24221-72
Form Liquid
Purity Protein A purified
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide.
Applications IHC-P, ICC/IF, Flow Cyt (Intra), WB
Key Features Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to DDX3; Suitable for: IHC-P, ICC/IF, Flow Cyt (Intra), WB; Reacts with: Mouse, Rat, Human

Target Information

Target Symbol DDX3X
Target Name ATP-dependent RNA helicase DDX3X
UniProt ID O00571
Cellular Localization Nucleus speckle. Cytoplasm. Located predominantly in nuclear speckles and, at low levels, throughout the cytoplasm. Located to the outer side of nuclear pore complexes (NPC). Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.
Function ATP-dependent RNA helicase. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. Also involved in HIV-1 replication. Interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.
Sequence Similarities Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.

Storage & Shipping

Storage Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage & Shipping Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

For research use only. Not for clinical use.