Anti-E2F4 Monoclonal Antibody (RMAB-0251400)
Cat. No.: RMAB-0251400
Category: Primary Antibodies
Research Area: Stem Cells, Epigenetics
INQUIRY
100 μL
Customer Size
Anti-E2F4 Monoclonal Antibody. Tested in IF, WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to Human E2F4. |
| Applications | WB, IHC, IF, ICC |
Target Information
| Target Symbol | E2F4 |
|---|---|
| Target Name | Transcription factor E2F4 |
| UniProt ID | Q16254 |
| Developmental Stage | Present in the growth-arrested state, its abundance does not change significantly as cells move into and through the cell cycle. |
| Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein. |
| Post-translational Modifications | Differentially phosphorylated in vivo. |
| Sequence Similarities | Belongs to the E2F/DP family. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
