Anti-GCSF Receptor Antibody (RMAB-0250623)
Cat. No.: RMAB-0250623
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to GCSF Receptor
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR8957 |
| Form | Liquid |
| Purity | Tissue culture supernatant |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | Flow Cyt (Intra), WB, Indirect ELISA |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to GCSF Receptor; Suitable for: Flow Cyt (Intra), WB, Indirect ELISA; Reacts with: Human |
Target Information
| Target Symbol | CSF3R |
|---|---|
| Target Name | Granulocyte colony-stimulating factor receptor |
| UniProt ID | Q99062 |
| Cellular Localization | Secreted and Cell membrane. |
| Function | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. |
| Involvement in Disease | Hereditary neutrophilia |
| Domain | The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The box 1 motif is required for JAK interaction and/or activation. |
| Sequence Similarities | Belongs to the type I cytokine receptor family. Type 2 subfamily. Contains 5 fibronectin type-III domains. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at -20°C. |
For research use only. Not for clinical use.
