Anti-HES5 Antibody (RMAB-0250707)
Cat. No.: RMAB-0250707
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to HES5
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR15578 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant fragment. |
| Applications | IHC-P, WB, IP |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to HES5; Suitable for: IHC-P, WB, IP; Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | HES5 |
|---|---|
| Target Name | Transcription factor HES-5 |
| UniProt ID | Q5TA89 |
| Cellular Localization | Nucleus. |
| Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. |
| Domain | Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins. |
| Sequence Similarities | Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 Orange domain. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol, 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
