Anti-HuD Antibody (RMAB-0250721)
Cat. No.: RMAB-0250721
Category: Primary Antibodies
INQUIRY
100 μL
10 µL
Rabbit monoclonal to HuD
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR26472-54 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | IP, IHC-P, Flow Cyt (Intra), WB, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to HuD; Suitable for: IP, IHC-P, Flow Cyt (Intra), WB, ICC/IF; Reacts with: Human |
Target Information
| Target Symbol | ELAVL4 |
|---|---|
| Target Name | ELAV-like protein 4 |
| UniProt ID | P26378 |
| Function | May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA. |
| Post-translational Modifications | Methylation at Arg-243 by CARM1 weakens protective binding to the 3'-UTR of CDKN1A mRNA and down-regulates CDKN1A protein expression, thereby maintaining cells in a proliferative state. Methylation is inhibited by NGF, which facilitates neurite outgrowth. |
| Sequence Similarities | Belongs to the RRM elav family. Contains 3 RRM (RNA recognition motif) domains. |
Storage & Shipping
| Storage Buffer | pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
