Anti-Integrin alpha 4 ITGA4 Rabbit Monoclonal Antibody (RMAB-0251500)
Cat. No.: RMAB-0251500
Category: Primary Antibodies
Research Area: Immunology, Stem Cells
INQUIRY
100 μL
Customer Size
Anti-Integrin alpha 4 ITGA4 Rabbit Monoclonal Antibody. Tested in WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Applications | WB, Flow Cyt, IHC, IF, ICC |
Target Information
| Target Symbol | ITGA4 |
|---|---|
| Target Name | Integrin alpha-4 |
| UniProt ID | P13612 |
| Function | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
