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Anti-nkx6.1 Antibody (RMAB-0250912)

Cat. No.: RMAB-0250912

Category: Primary Antibodies

INQUIRY 100 μL Customer Size
Rabbit monoclonal to nkx6.1

Product Features

Isotype IgG
Clonality Monoclonal
Host Species Rabbit
Clone Number EPR20328
Form Liquid
Purity Protein A purified
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide.
Applications WB, IHC-P
Key Features Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to nkx6.1; Suitable for: WB, IHC-P; Reacts with: Mouse, Rat, Human

Target Information

Target Symbol NKX6-1
Target Name Homeobox protein Nkx-6.1
UniProt ID P78426
Cellular Localization Nucleus.
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.
Domain The C-terminal domain contributes to sequence-specific DNA-binding.
Sequence Similarities Contains 1 homeobox DNA-binding domain.

Storage & Shipping

Storage Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage & Shipping Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

For research use only. Not for clinical use.