Anti-Integrin alpha 6 ITGA6 Rabbit Monoclonal Antibody (RMAB-0250759)
Cat. No.: RMAB-0250759
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Key Features | Bio Anti-Integrin alpha 6 ITGA6 Rabbit Monoclonal Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. |
Target Information
| Target Symbol | ITGA6 |
|---|---|
| Target Name | Integrin alpha-6 |
| UniProt ID | P23229 |
| Function | Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:2682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:2235176). |
| Involvement in Disease | Epidermolysis bullosa letalis, with pyloric atresia |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
