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Anti-KLF4 Antibody - BSA and Azide free (Detector)

Anti-KLF4 Antibody - BSA and Azide free (Detector) (RMAB-0252087)

Cat. No.: RMAB-0252087

Category: Antibody Pair

INQUIRY 100 μg 1 mg
Rabbit monoclonal to KLF4 - BSA and Azide free (Detector)

Product Features

Isotype IgG
Clonality Monoclonal
Host Species Rabbit
Clone Number EPR22833-30
Form Liquid
Species Reactivity Mouse, Rat
Applications Sandwich ELISA
Key Features Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to KLF4 - BSA and Azide free (Detector); Suitable for: Sandwich ELISA; Reacts with: Mouse, Rat

Target Information

Target Symbol KLF4
Target Name Krueppel-like factor 4
UniProt ID O43474
Cellular Localization Nucleus.
Function Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
Domain the 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
Sequence Similarities Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers.

Storage & Shipping

Storage Buffer Constituent: 100% PBS
Storage & Shipping Shipped at 4°C. Store at 4°C.

For research use only. Not for clinical use.