Anti-KLF4 Antibody - BSA and Azide free (Detector) (RMAB-0252087)
Cat. No.: RMAB-0252087
Category: Antibody Pair
INQUIRY
100 μg
1 mg
Rabbit monoclonal to KLF4 - BSA and Azide free (Detector)
Product Features
Isotype | IgG |
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Clonality | Monoclonal |
Host Species | Rabbit |
Clone Number | EPR22833-30 |
Form | Liquid |
Species Reactivity | Mouse, Rat |
Applications | Sandwich ELISA |
Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to KLF4 - BSA and Azide free (Detector); Suitable for: Sandwich ELISA; Reacts with: Mouse, Rat |
Target Information
Target Symbol | KLF4 |
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Target Name | Krueppel-like factor 4 |
UniProt ID | O43474 |
Cellular Localization | Nucleus. |
Function | Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. |
Domain | the 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. |
Sequence Similarities | Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. |
Storage & Shipping
Storage Buffer | Constituent: 100% PBS |
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Storage & Shipping | Shipped at 4°C. Store at 4°C. |
For research use only. Not for clinical use.