Anti-MAP2 Antibody (RMAB-0250837)
Cat. No.: RMAB-0250837
Category: Primary Antibodies
INQUIRY
25 μL
Customer Size
Chicken polyclonal to MAP2
Product Features
| Isotype | IgY |
|---|---|
| Clonality | Polyclonal |
| Host Species | Chicken |
| Form | Liquid |
| Species Reactivity | Mouse, Rat |
| Immunogen | Recombinant fragment corresponding to Human MAP2. Mix of recombinant human constructs of projection domain sequences, amino acids 235-1588. |
| Applications | ICC, IHC-P, WB |
| Key Features | Chicken polyclonal to MAP2; Suitable for: ICC, IHC-P, WB; Reacts with: Mouse, Rat; Isotype: IgY |
Target Information
| Target Symbol | MAP2 |
|---|---|
| Target Name | Microtubule-associated protein 2 |
| UniProt ID | P11137 |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Function | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
| Post-translational Modifications | Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. |
| Sequence Similarities | Contains 3 Tau/MAP repeats. |
Storage & Shipping
| Storage Buffer | Preservative: 0.032% Sodium azide; Constituent: PBS |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C. Do Not Freeze. |
For research use only. Not for clinical use.
