Anti-nkx6.1 Antibody (RMAB-0250913)
Cat. No.: RMAB-0250913
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to nkx6.1
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR20405 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse |
| Immunogen | Recombinant fragment. |
| Applications | IHC-Fr, WB, IHC-P |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to nkx6.1; Suitable for: IHC-Fr, WB, IHC-P; Reacts with: Mouse, Human |
Target Information
| Target Symbol | NKX6-1 |
|---|---|
| Target Name | Homeobox protein Nkx-6.1 |
| UniProt ID | P78426 |
| Cellular Localization | Nucleus. |
| Function | Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. |
| Domain | The C-terminal domain contributes to sequence-specific DNA-binding. |
| Sequence Similarities | Contains 1 homeobox DNA-binding domain. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: PBS, 40% Glycerol, 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
