Anti-RBPJK Monoclonal Antibody (RMAB-0251521)
Cat. No.: RMAB-0251521
Category: Primary Antibodies
Research Area: Stem Cells, Epigenetics, Neuroscience
INQUIRY
100 μL
Customer Size
Anti-RBPJK Monoclonal Antibody. Tested in IF, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide. |
| Applications | WB, IHC, IF, ICC, IP |
Target Information
| Target Symbol | RBPJ |
|---|---|
| Target Name | Recombining binding protein suppressor of hairless |
| UniProt ID | Q06330 |
| Function | Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. |
| Sequence Similarities | Belongs to the Su(H) family. Contains 1 IPT/TIG domain. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
