Anti-ROR2 Antibody (RMAB-0251007)
Cat. No.: RMAB-0251007
Category: Primary Antibodies
INQUIRY
100 μg
Customer Size
Mouse monoclonal to ROR2
Product Features
| Isotype | IgG1 |
|---|---|
| Clonality | Monoclonal |
| Host Species | Mouse |
| Clone Number | Nt 2535-2835 |
| Form | Liquid |
| Purity | Protein G purified |
| Species Reactivity | Human, Rat |
| Immunogen | Fusion protein. |
| Applications | WB, IHC-P |
| Key Features | Mouse monoclonal to ROR2; Suitable for: WB, IHC-P; Knockout validated; Reacts with: Rat, Human; Isotype: IgG1 |
Target Information
| Target Symbol | ROR2 |
|---|---|
| Target Name | Tyrosine-protein kinase transmembrane receptor ROR2 |
| UniProt ID | Q01974 |
| Cellular Localization | Cell membrane. |
| Developmental Stage | Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. |
| Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. |
| Involvement in Disease | Brachydactyly B1Robinow syndrome autosomal recessive |
| Sequence Similarities | Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. Contains 1 FZ (frizzled) domain. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 kringle domain. Contains 1 protein kinase domain. |
Storage & Shipping
| Storage Buffer | pH: 7.40; Preservative: 0.02% Sodium azide; Constituent: PBSSome batches contain 6.97% L-Arginine as a stabilizing agent. For lot-specific buffer information, please contact our Scientific Support team. |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Store at -20°C. |
For research use only. Not for clinical use.
