Anti-SFRP4 Antibody (RMAB-0251030)
Cat. No.: RMAB-0251030
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to SFRP4
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR9389 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide. |
| Applications | WB, IHC-P, Flow Cyt (Intra), ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to SFRP4; Suitable for: WB, IHC-P, Flow Cyt (Intra), ICC/IF; Reacts with: Mouse, Human |
Target Information
| Target Symbol | SFRP4 |
|---|---|
| Target Name | Secreted frizzled-related protein 4 |
| UniProt ID | Q6FHJ7 |
| Cellular Localization | Secreted. Cytoplasmic in ovarian tumor cells. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
| Domain | The FZ domain is involved in binding with Wnt ligands. |
| Sequence Similarities | Belongs to the secreted frizzled-related protein (sFRP) family. Contains 1 FZ (frizzled) domain. Contains 1 NTR domain. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at -20°C. |
For research use only. Not for clinical use.
