Anti-Smad1 Rabbit Monoclonal Antibody (RMAB-0251352)
Cat. No.: RMAB-0251352
Category: Primary Antibodies
Research Area: Cancer Research, Stem Cells, Epigenetics, Metabolism
INQUIRY
100 μL
Customer Size
Anti-Smad1 Rabbit Monoclonal Antibody. Tested in IF, WB applications. This antibody reacts with Human.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Applications | WB, IF, ICC |
Target Information
| Target Symbol | SMAD1 |
|---|---|
| Target Name | Mothers against decapentaplegic homolog 1 |
| UniProt ID | Q15797 |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP3 repressor SNIP1. |
| Post-translational Modifications | Phosphorylated on serine by BMP type 1 receptor kinase. Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1. |
| Sequence Similarities | Belongs to the dwarfin/SMAD family. Contains 1 MH1 (MAD homology 1) domain. Contains 1 MH2 (MAD homology 2) domain. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
