Biotinylated Anti-Murine FGF-9 Polyclonal Antibody (RMAB-0251583)
Cat. No.: RMAB-0251583
Category: Primary Antibodies
INQUIRY
25 μg
50 μg
Product Features
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Immunogen | E.coli derived Recombinant Murine FGF-9 |
Target Information
| Target Symbol | FGF9 |
|---|---|
| Target Name | Fibroblast growth factor 9 |
| UniProt ID | P31371 |
| Cellular Localization | Secreted. |
| Function | Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. |
| Involvement in Disease | Multiple synostoses syndrome 3 (SYNS3): A bone disease characterized by multiple progressive joint fusions that commonly involve proximal interphalangeal, tarsal-carpal, humeroradial and cervical spine joints. Additional features can include progressive conductive deafness and facial dysmorphism. The disease is caused by variants affecting the gene represented in this entry. |
| Post-translational Modifications | Three molecular species were found (3 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 3 kDa species which is uncleavable in the secretion step. N-glycosylated. |
| Sequence Similarities | Belongs to the heparin-binding growth factors family. |
For research use only. Not for clinical use.
