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Chloroquine diphosphate, apoptosis and autophagy inhibitor

Chloroquine diphosphate, apoptosis and autophagy inhibitor (RMML-00120103)

Cat. No.: RMML-00120103

Category: Inhibitors & Activators

INQUIRY 500 mg 100 mg
Antimalarial; apoptosis and autophagy inhibitor

Product Features

Source Synthetic
Purity > 98%
Key Features Antimalarial; apoptosis and autophagy inhibitor; CAS Number: 50-63-5; Purity: > 98%; Soluble in water to 100 mM; Form / State: Solid; Source: Synthetic

Compound Information

Target Pathways Apoptosis, autophagy
Biological Description Antimalarial agent. Inhibits tumor cell growth and metastasis and induces apoptosis in vitro. Binds to Fe(II)-protoporphyrin IX (FP) to form FP-chloroquine complex resulting in cell lysis and parasite cell autodigestion.
CAS Number 50-63-5
Chemical Name N4-(7-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine diphosphate
SMILES CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O
Molecular Formula C18H26ClN3.2H3PO4
Molecular Weight 515.87 Da
PubChem Identifier 64927

Storage & Shipping

Handling Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information.
Solubility Soluble in water to 100 mM
Storage & Shipping Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

For research use only. Not for clinical use.