Cilostamide, PDE3 inhibitor (RMML-00120819)
Cat. No.: RMML-00120819
Category: Inhibitors & Activators
INQUIRY
50 mg
10 mg
Potent, selective PDE3 inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent, selective PDE3 inhibitor; CAS Number: 68550-75-4; Purity: > 98%; Soluble in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | PDE3 |
|---|---|
| Biological Description | Potent, selective PDE3 inhibitor (IC50 values are 27 and 50 nM for PDE3A and PDE3B, respectively). Inhibits ADP-induced platelet aggregation (IC50 = 16.8 μM). Antithrombotic effects in vivo. Orally active. |
| CAS Number | 68550-75-4 |
| Chemical Name | N-Cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methylbutanamide |
| SMILES | CN(C1CCCCC1)C(=O)CCCOc2ccc3NC(=O)C=Cc3c2 |
| Molecular Formula | C20H26N2O3 |
| Molecular Weight | 342.44 Da |
| PubChem Identifier | 2753 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM |
| Storage & Shipping | Store at room temperature. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
