Curcumin (Diferuloylmethane), Lipooxygenase inhibitor (RMML-00120317)
Cat. No.: RMML-00120317
Category: Inhibitors & Activators
INQUIRY
250 mg
50 mg
Flavonoid. Lipooxygenase inhibitor. Antioxidant, anti-inflammatory agent.
Product Features
| Source | Synthetic |
|---|---|
| Key Features | Flavonoid. Lipooxygenase inhibitor. Antioxidant, anti-inflammatory agent.; CAS Number: 458-37-7; Soluble in ethanol to 10 mM and in DMSO to 10 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | Lipooxygenase |
|---|---|
| Biological Description | Flavonoid derived from Curcuma longa plant. Potent antioxidant, anti-inflammatory, analgesic and anticancer agent. Lipooxygenase and cyclooxygenase inhibitor (IC50 values are 8 and 52 μM, respectively). Blood-brain barrier permeable. Shows diverse range of actions including free radical scavenging activity in vitro and in vivo, cardio and neuroprotective effects. |
| Alternative Names | Diferuloylmethane |
| CAS Number | 458-37-7 |
| Chemical Name | (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione |
| SMILES | COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O |
| Molecular Formula | C21H20O6 |
| Molecular Weight | 368.38 Da |
| PubChem Identifier | 969516 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. |
|---|---|
| Solubility | Soluble in ethanol to 10 mM and in DMSO to 10 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
