Y-27632 (Dihydrochloride) (RMML-00121103)
Cat. No.: RMML-00121103
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
Y-27632 is a cell-permeable, highly potent and selective inhibitor of Rho-associated, coiled-coil containing protein kinase. LEnhances survival of human embryonic stem. Improves embryoid body formation using forced-aggregation protocols. Increases the survival of cryopreserved single human ES cells after thawing. Blocks apoptosis of mouse ES-derived neural precursors after dissociation and transplantation. Direct lineage reprogramming of fibroblasts to mature neurons, in combination with CHIR99021, RepSox, Forskolin, SP600125, Gö6983 and Valproic Acid. Improves survival of human ES cell monolayers at the initiation of differentiation protocols
Product Features
| Purity | ≥ 98% |
|---|---|
| Applications | Differentiation, Expansion, Maintenance, Reprogramming, Spheroid Culture |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | RHO/ROCK |
|---|---|
| Alternative Names | ROCK inhibitor |
| CAS Number | 129830-38-2 |
| Molecular Formula | C₁₄H₂₁N₃O 2HCl |
| Molecular Weight | 320.3 Da |
Storage & Shipping
| Handling | Refer to SDS for further information. |
|---|
For research use only. Not for clinical use.
