Cyclopamine (ethanol solution), Hh signaling inhibitor (RMML-00120396)
Cat. No.: RMML-00120396
Category: Inhibitors & Activators
INQUIRY
5 mg
Hh signaling inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 99% |
| Key Features | Hh signaling inhibitor; CAS Number: 4449-51-8; Purity: > 99%; Supplied in ethanol (10 mM); Form / State: Liquid; Source: Synthetic |
Compound Information
| Target Pathways | Hh |
|---|---|
| Biological Description | Cell-permeable inhibitor of hedgehog (Hh) signaling, via direct inhibition of Smo (Smoothened), the accessory protein to the putative Hh receptor. Anticancer and teratogenic activity in vivo. |
| CAS Number | 4449-51-8 |
| Chemical Name | (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro- 3',6,10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'( 3'H)-furo[3,2-b]pyridin]-3-ol |
| SMILES | CC4=C5C[C@@H]1[C@@]6(C)CC[C@H](O)CC6=CC[C@H]1[C@@H]5CC[C@@]24O[C@@H]3C[C@H](C)CN[C@H]3[C@H]2C |
| Molecular Formula | C27H41NO2 |
| Molecular Weight | 411.63 Da |
| PubChem Identifier | 442972 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. |
|---|---|
| Solubility | Supplied in ethanol (10 mM) |
| Storage & Shipping | Store at -20°C. Store in the dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. |
For research use only. Not for clinical use.
