DMPQ dihydrochloride, PDGFR beta inhibitor (RMML-00120740)
Cat. No.: RMML-00120740
Category: Inhibitors & Activators
INQUIRY
50 mg
10 mg
Potent and selective PDGFRβ inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 99% |
| Key Features | Potent and selective PDGFRβ inhibitor; CAS Number: 1123491-15-5; Purity: > 99%; Soluble in water to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | PDGFR beta |
|---|---|
| Biological Description | Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.Also available in simple stock solutions (ab146732) - add 1 mL of water to get an exact, ready-to-use concentration. |
| CAS Number | 1123491-15-5 |
| Chemical Name | 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride |
| SMILES | Cl.Cl.COc1cc(OC)nc2ccc(cc12)c3ccncc3 |
| Molecular Formula | C16H14N2O2.2HCl |
| Molecular Weight | 339.22 Da |
| PubChem Identifier | 45073427 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. |
|---|---|
| Solubility | Soluble in water to 100 mM |
| Storage & Shipping | Store at room temperature. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
