Honokiol

Reduce production of inflammatory factors with honokiol, a natural lignan. Derived from the plant Magnolia grandiflora, honokiol possesses antineoplastic and neuroprotective properties. Honokiol inhibits the phosphorylation of Akt, a protein kinase that plays a role in regulating the production of inflammatory molecules. Honokiol has been used for:Induces apoptosis in various. Reduces inflammation and senescence-associated biomarkers in cigarette smoke-damaged skin cells in vitro. Blocks in vitro angiogenesis and in vivo tumor growth. Promotes neurite growth and enhances survivability in rat cortical neurons. Protects rat cerebellar granule neurons from glutamate- and N-methyl-D-aspartate. Induces anti-cardiac hypertrophic effects in vitro and in mice by activating mitochondrial SIRT3.